Cas No.74381-53-6

Sequence:Glp-His-Trp-Ser-Tyr-DLeu-Leu-Arg-Pro-NHEt

₅₉H₈₄N₁₆O_{12· 2}H₄O₂(n=1~2)

Molar Mass:1209.4·n60.02

The Maximum Unspecified Impurity : Less than or equal to 0.2%

Packing Size:20G/Bottle,40G/Bottle or at customers reqirement.

53714-56-0 (net), 74381-53-6 (acetate)

C59H84N16O12
1209.41
Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt

is a synthetic 9 residue peptide analog of gonadotropin releasing hormone belonging to the class of drugs called hormones or hormone antagonists. It is used to treat advanced prostate cancer, uterine fibroids, and endometriosis (under investigation for possible use in the treatment of mild to moderate Alzheimer's disease). Leuprolide is also used to treat precocious puberty, control ovarian stimulation in in vitro fertilization (IVF), and for reducing sexual urges in pedophiles and other cases of paraphilia.

Primarily degraded by peptidase (instead of cytochrome P450 enzymes).

Excretion in urine, 8.34 L/hour [healthy male receiving a 1-mg IV bolus]

Beliebte label: